Novel 5,6,7,8-tetrahydrobenzo[b]pyran Derivatives: Synthesis and Anticancer Activity

نویسندگان

چکیده

Many new cyclized pyran systems with a potential anti-cancer activity were designed and prepared. Pyran showed high reactivity to various chemical reagents. 24 products of the prepared compounds chosen tested in (mM) as respectable anticancer factors. The findings revealed that 3b, 6b, 8 widely effective against three cancer cell lines including A-549 (lung carcinoma), HC-29 (colorectal adenocarcinoma), MKN-45 (gastric cancer) compared standard reference control foretinib.

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ژورنال

عنوان ژورنال: Acta Chimica Slovenica

سال: 2023

ISSN: ['1318-0207', '1580-3155']

DOI: https://doi.org/10.17344/acsi.2022.7893